8
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是的,在统计学上有显著的合并症与自身免疫性疾病。
该研究 Recent Insights in the Epidemiology of Autoimmune Diseases: 改进的流行病率估计和疾病聚类的理解分析了其他有关该主题的研究。
早期的研究将29种自身免疫性疾病–包括克罗恩氏症、糖尿病、类风湿性关节炎等–的并发症率约为7%至9%。反之亦然,几项被分析的研究报告称,类风湿性关节炎合并多发性硬化症的发生频率低于预期。
关于这个问题的另外两项主要的meta分析是
1.Are Individuals With an Autoimmunmune Disease at Higher Risk of a Second Autoimmune Disorder? 在美国流行病学杂志 2. Autoimmune diseases co-curring within individuals and within families: a systematic review ](http://www.ncbi.nlm.nih.gov/pubmed/16477262) in the journal Epidemiology
The conclusion that a significant comorbidity exists and that it’s more prevalent between certain diseases is drawn by all these studies the studies, which is also discussed in the first paper I linked.